2-Boc-5-oxo-hexahydrocyclopenta[c]pyrrole

2-Boc-5-oxo-hexahydrocyclopenta[c]pyrrole - Names and Identifiers

Name	cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester
Synonyms	2-Boc-5-oxo-hexahydrocyclopenta[c]pyrrole tert-Butyl 5-oxo-octahydrocyclopenta-[c]pyrrole-2-carboxylate tert-butyl cis-5-oxo-octahydrocyclopenta[c]pyrrole-2-carboxylate cis-tert-Butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester (3aR,6aS)-5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester (3aR,6aS)-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid 1,1-dimethylethyl ester Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-oxo-, 1,1-dimethylethyl ester, (3aR,6aS)-rel-
CAS	146231-54-1

2-Boc-5-oxo-hexahydrocyclopenta[c]pyrrole - Physico-chemical Properties

Molecular Formula	C12H19NO3
Molar Mass	225.28
Density	1.139±0.06 g/cm3(Predicted)
Boling Point	325.8±35.0 °C(Predicted)
pKa	-0.82±0.20(Predicted)
Storage Condition	2-8°C
Sensitive	Irritant
MDL	MFCD11616063

2-Boc-5-oxo-hexahydrocyclopenta[c]pyrrole - Introduction

cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester (abbreviated as DIBOC) is an organic compound. It is a white crystalline solid with a low melting and boiling point.

DIBOC is widely used as a protecting group in organic synthesis to protect hydroxyl groups (such as alcohols and phenols) to prevent unnecessary reactions. It can form a stable Ester structure by reacting with the hydroxyl group, and the original hydroxyl group can be restored by the reaction of the protective agent when necessary.

The method of preparing DIBOC is usually by reacting carboxylic acid with tosyl chloride (TsCl) to obtain a carboxylic acid sulfonyl Ester, and then reacting it with tert-butyl alcohol to form DIBOC.

Regarding safety information, DIBOC is a chemical and needs to be handled with care. It can cause irritation to the skin and eyes. Appropriate personal protective measures should be taken during use, such as wearing gloves and goggles. In addition, during storage and handling, it is necessary to keep away from ignition and oxidizing agents to avoid fire or explosion accidents.

Last Update：2024-04-09 20:52:54